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Korean J Parasitol > Volume 21(2):1983 > Article

Original Article
Korean J Parasitol. 1983 Dec;21(2):167-186. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1983.21.2.167
Copyright © 1983 by The Korean Society for Parasitology
Epidemiological studies on Clonorchis sinensis infection along the Nam-river in Gyeongnam province, Korea
Kyoung-Hoon Bae,Yung-Kyum Ahn,*Chin-Thack Soh and Hiroshi Tsutsumi
Instiutue of Tropical Medicine, Yonsei University, Seoul, Korea.
*Wonju Medical College, Yonsei University, Kangwon-do, Korea.
Kurume University, School of Medicine, Japan.
Abstract

The prevalence of C. sinensis infection along the Nam river, Korea, was 38.7% of 5,291 people examined. Prevalence rates varied from 42% at the upper stream to 34% at the middle stream and 40% at the down stream region. Rates were highest (53.4-54.3%) in the 30-59 years of age group. The positive rates in primary school chidren, school students, teachers and local officers, and other inhabitants were 16.5%, 22.6%, 46.2% and 49.6% respectively. 53.6% of cases were light infected, i.e. less than 4,000/EPG. The cercarial expulsion rate of 5,005 Parafossarulus sp. was 0.34%. Snails naturally infected with C. sinensis expelled about 788 cercariae/day. Ten of 18 species of freshwater fish examined had C. sinensis metacercariae. To prevent clonorchiasis in the endemic areas, the effective health education system is suggested as a control measure.

Figures


Fig. 1
Surveyed regions of the Nam-river.


Fig. 2
Comparison of infected intensity by EPG of Clonorchis sinensis according to sex.


Fig. 3
Prevalence and intensity of Clonorchis sinensis infections by sex and age.


Fig. 4
Pathological observation of Parafossarulus snail infected with Clonorchis sinensis and Loxogenes liberum. 1. Liver tissue of snail infected with C. sinensis. 2. Higher magnification of the No. 1. 3. Infected with Loxogenes liberum. 4. Higher magnification of the No. 3.


Fig. 5
Expelled cercariae of Clonorchis sinensis from naturally infected Parafossarulus snail in a day.

Tables


Table 1
Regional comparison of positive rates of Clonorchis sinensis by sex along the Nam-river, Gyeongnam Province


Table 2
Regional prevalences of helminths in area along the Nam-river, Gyeongnam Province, Korea


Table 3
Prevalence of Clonorchis sinensis infection by sex and age along the Nam-river, Gyeongnam Province


Table 4
Prevalence of Clonorchis sinensis infection by social strata in surveyed regions along the Nam-river, Gyeongnam Province


Table 5
Prevalence of Clonorchis sinensis infection by administrative district (Gun=County) along the Nam-river, Gyeongnam Province


Table 6
Infected intensity by EPG count of Clonorchis sinensis along the Nam-river, Gyeongnam Province


Table 7
EPG distribution of Clonorchis sinensis infections by sex and age among inhabitants in area along the Nam-river, Gyeongnam Province


Table 8
Regional intensity of Clonorchis sinensis infection by EPG count among inhabitants in area along the Nam-river, Gyeongnam Province


Table 9
Comparison of positive rates of Clonorchis sinensis and Metagonimus yokogawai along the Nam-river area


Table 10
Distribution of Parafossarulus manchouricus snail and cercarial incidence of Clonorchis sinensis along the Nam-river in Gyeongnam Province


Table 11
Expelled cercariae of Clonorchis sinensis from naturally infected Parafossarulus snail in a day


Table 12
Mean number of expelled cercariae of Clonorchis sinensis from Parafossarulus snails


Table 13
Kinds of expelled cercariae from Parafossarulus snails infected with trematodes


Table 14
Comparison of expelled cercariae of various trematodes from naturally infected Parafossarulus snails in 5 days


Table 15
Detection rate of Clonorchis metacercaria in the fresh-water fishes caught (or purchased) along the Nam-river area


Table 16
Metacercarial density of Pseudorasbora parva caught at the Jinyang lake side

References
1. Ahn YK, et al. Yonsei Rept Trop Med 1981;12:11–16.
2. Bϋhring KU, et al. Europ J Drug Metabol & Pharm 1978;3:179–190.
3. Chi LW, Winkler LR. The effects of copper sulfate, sodium pentachlorophenate and a sulfonated hydrocarbon on the eggs of Oncomelania. Am J Trop Med Hyg 1962;11:851–854.
 
4. Cho KM, Kim CH, Ahn YK, Soh CT. Experimental Studies Of 1, 4-Bis-Trichlormethyl-Benzol On The Infection Of Clonorchis Sinensis(I). Korean J Parasitol 1966;4(1):11–20.
 
5. Cho MJ, Cho KM, Soh CT. The Use Of Hetol On The Infection Of Clonorchis Sinensis. Korean J Parasitol 1966;4(1):21–31.
 
6. Choi DW. Clonorchis sinensis in Kyungpook province, Korea: 2. Demonstration of metacercaria of Clonorchis sinensis from fresh-water fish. Korean J Parasitol 1976;14(1):10–16.
 
7. Choi DW, Ahn DH, Choy CH, Kim SS. Clonorchis Sinensis In Kyungpook Province, Korea: 3. Changing Pattern Of Clonorchis Sinensis Infection Among Inhabitants. Korean J Parasitol 1976;14(2):117–122.
 
8. Chun SK. Bull Pusan Fisheries Coll 1962;4:21–38.
9. Chun SK. Bull Pusan Fisheries Coll 1965;6:99–106.
10. Chung BJ, Joo CY, Choi DW. Seasonal variation of snail population of Parafossarulus manchouricus and larval trematode infection in river Kumho, Kyungpook province, Korea. Korean J Parasitol 1980;18(1):54–64.
 
11. Faust EC, et al. Clonorchis sinensis Am J Hyg 1927;8:1–248.
12. Seo BS, Hong NT. Study On Metagonimus Yokogawai(Katsurada, 1912) In Korea: I. On The Metacercaria, Its Distribution In The Second Intermediate Host And The Development In The Final Host. Korean J Parasitol 1969;7(3):129–142.
 
13. Joo CY, Choi DW. Newly found endemic foci of Clonorchis sinensis in Kyungpook Province, Korea. Korean J Parasitol 1974;12(2):111–118.
 
14. Kang SY, Loh IK, Chun YS, Lim DS. [A Study On The Chemotherapy In Clonorchiasis: Report 1. An Experimental Study On Chemotherapy With Dithiazanine Iodide And Bithionol Sulfoxide In Clonorchiasis]. Korean J Parasitol 1965;3(1):19–30.
 
15. Kim DC, Lee OY, Jeong EB. [Epidemiological conditions of Metagonimus yokogawai infection in Hadong Gun, Gyeongsang Nam Do]. Korean J Parasitol 1979;17(1):51–59.
 
16. Kim DC, et al. Ann Report of N.I.H. Korea 1968;5:152–155.
17. Kim DC. Yonsei Rept Trop Med 1974;5:3–44.
18. Kim JM. [Studies on the molluscicidal and cercariacidal effects of various pesticides in liver fluke]. Korean J Parasitol 1965;3(3):86–106.
 
19. Kim CH. [Study on the Metagonimus sp. in Gum river basin, Chungchung-nam Do, Korea]. Korean J Parasitol 1980;18(2):215–228.
 
20. Kim SH. Theses Kong Ju Teachers Coll 1965;2:81–85.
21. Kim SH. Theses Kong Ju Teachers Coll 1966;3:173–178.
22. Kim SH, et al. Rural Health 1952;1:51–55.
23. Kobayashi H. Mitt Med Hosch zu Keijo 1924;7:1–10.
24. Kagan KG, et al. J Parasit 1964;50:474.
 
25. Komiya T, et al. Progress of Medical Parasitology in Japan 1964;1:551–600.
26. Lee JT. [Studies on the metacercariae from fresh water fishes in the Kum-Ho River]. Korean J Parasitol 1968;6(3):77–99.
 
27. Lee JS, Jin SW, Rim HJ. [Egg-Laying Capacity Of Clonorchis Sinensis In Guinea Pig And Rabbit]. Korean J Parasitol 1979;17(1):81–85.
 
28. Lee SK, et al. Kyungpook Univ Med J 1958;1:9–14.
29. Lie KJ, Heyneman D, Kostanian N. Failure of Echinostoma lindoense to reinfect snails already harboring that species. Int J Parasitol 1975;5(5):483–486.
  
30. Lie KJ, Heyneman D. Studies on resistance in snails: a specific tissue reaction to Echinostoma lindoense in Biomphalaria glabrata snails. Int J Parasitol 1975;5(6):621–625.
  
31. Lie KJ, Heyneman D. Studies on resistance in snails. 3. Tissue reactions to Echinostoma lindoense sporocysts in sensitized and resensitized Biomphalaria glabrata. J Parasitol 1976;62(1):51–58.
  
32. Leopold G, Ungethüm W, Groll E, Diekmann HW, Nowak H, Wegner DH. Clinical pharmacology in normal volunteers of praziquantel, a new drug against schistosomes and cestodes. An example of a complex study covering both tolerance and pharmacokinetics. Eur J Clin Pharmacol 1978;14(4):281–291.
  
33. Olivier L, Haskins WT. The effects of low concentrations of sodium pentachlorophenate on the fecundity and egg viability of Australorbis glabratus. Am J Trop Med Hyg 1960;9:199–205.
 
34. Ritchie LS. Bull US Army Med Dept 1948;8:326.
35. Rim HJ, Lyu KS, Lee JS, Joo KH. Clinical evaluation of the therapeutic efficacy of praziquantel (Embay 8440) against Clonorchis sinensis infection in man. Ann Trop Med Parasitol 1981;75(1):27–33.
 
36. Rim HJ, Lee YM, Lee JS, Joo KH. Therapeutic field trial with praziquantel (Biltricide(R)) in a rural population infected with Clonorchis sinensis. Korean J Parasitol 1982;20(1):1–8.
 
37. Soh CT, et al. Yonsei Rept Trop Med 1975;6:14–22.
38. Soh CT, et al. Yonsei Rept Trop Med 1976;7:3–16.
39. Soh CT, et al. Yonsei Rept Trop Med 1977;8:72–78.
40. Soh CT, et al. Yonsei Rept Trop Med 1979;10:22–28.
41. Soh CT, et al. Yonsei Rept Trop Med 1980;11:51–57.
42. Soh CT, et al. Yonsei Rept Trop Med 1980;11:1–13.
43. Soh CT, Ahn YK. [Epidemiological Study On Metagonimus Yokogawai Infection Along Boseong River In Jeonra Nam Do, Korea]. Korean J Parasitol 1978;16(1):1–13.
 
44. Shin DS. [Epidemiological studies of Clonorchis sinensis prevailed in the peoples of Kyungpook Province]. Korean J Parasitol 1964;2(1):1–13.
 
45. Stoll NR, et al. Am J Hyg 1926;6:134–145.
46. Steiner K, et al. Europ J Drug Metabol & Pharm 1976;1:97–106.
 
47. WAlton BC, Winn MM, Williams JE. Development of resistance to molluscicides in Oncomelania nosophora. Am J Trop Med Hyg 1958;7(6):618–619.
 
48. Walton BC, Chyu I. Clonorchiasis and paragonimiasis in the Republic of Korea. Report on a prevalence survey using intradermal tests. Bull World Health Organ 1959;21:721–726.
 
49. Wykoff DE. Studies on Clonorchis sinensis. IV. Production of eggs in experimentally infected rabbits. J Parasitol 1959;45(1):91–94.
  
50. Yokogawa M, et al. J Parasit 1965;51:sect. 2.
51. Yeo TO, et al. Seoul J Med 1971;12:259–267.
52. Yun YS, et al. Korean Cent J Med 1975;29:361–369.
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