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Korean J Parasitol > Volume 4(2):1966 > Article

Original Article
Korean J Parasitol. 1966 Dec;4(2):1-6. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1966.4.2.1
Copyright © 1966 by The Korean Society for Parasitology
Clinical manifestation of Brugia malayi infection in Korea
Chin-Thack Soh,Keun-Tae Lee,Se-Wook Im and Jae-Heung Lee
Department of Parsitology, Yonsei University Medical College, Korea.

The clinical manifestations in filarial infection were examined during 1965-1966 from the known endemic areas: Yongju, a mountainous inland area and Cheju-Do, an island.

1. All the microfilaria which were found during the survey were Brugia malayi.

2. The principal symptom was cuticular hypertrophy (elephantiasis). It was found in 4 cases from Yongju among 707 villagers, 84 cases from Cheju-Do among 2,376 villagers.

3. Four microfilaremia cases (4.5%) were found among a total of 88 cases of elephantiasis.

4. In Cheju-Do, the higher incidence of elephantiasis was observed among people over 20 years old and the females showed much higher incidence than males (30 males and 54 females).

5. The cuticular hypertrophic changes (elephantiasis) appeared more often in the lower extremities(77%) than in the upper part of the body, and in the right side than in the left.


Endemic areas of filariasis in Korea

○ Previous surveyed areas

● Surveyed areas of present study

Hypertrophy of scrotum, 72 years old.


Table 1
Clinical manifestation of Brugia malayi infection in Yongju area

Table 2
Distribution of Elephantiasis By Age and Sex in Cheju-Do

Table 3
Onset of Elephantiasis by age in Cheju-Do

Table 4
Site of Elephantiasis in Chejudo

Table 5
Site and Number of Hypertrophic Changes in Two villages

1. Brug SL. Proc Roy Soc Med 1931;24:23.
2. Bun IJ. Chosen Med Assoc J 1939;29:697.
3. Bun IJ. Chosen Med Assoc J 1939;29:1426.
4. Gwang CH, et al. The Korean Central J of Med 1965;9:491.
5. Iyenger MOT. Ind Med Res Mem 1938;30:179.
6. Katamine D. Rynsho-to-Kenkyu 1954;31:36.
7. Lee KT. Bulletin of National Institute of Health, ROK 1961;4:107.
8. Kee KT, et al. J Korean Med Assoc 1964;7:657.
9. Oh HY. The China Med J 1929;43:16.
10. Oh SN. Mansen-no-Ikai 1930;120:25.
11. Rao SS. Ind Med Res Mem 1945;30:179.
12. Senoo T. Japanese J Parasitology 1943;15:36.
13. Yun IS. Chosen Med Assoc J 1927;76:326.
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