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Korean J Parasitol > Volume 32(3):1994 > Article

Brief Communication
Korean J Parasitol. 1994 Sep;32(3):201-204. English.
Published online Sep 20, 1994.  http://dx.doi.org/10.3347/kjp.1994.32.3.201
Copyright © 1994 by The Korean Society for Parasitology
A case of echinostomiasis with ulcerative lesions in the duodenum
J Y Chai,*1S T Hong,1S H Lee,1G C Lee,2 and Y I Min2
1Department of Parasitology and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110-799, Korea.
Received July 09, 1994; Accepted August 04, 1994.


Echinostomiasis is an endemic intestinal trematodiasis of humans in Korea. We observed a human case of Echinostoma hortense infection who had ulcerations on the duodenal mucosa. A 55-year old man living in Hamyang-gun, Kyongnam, complained of epigastric pain with hematemesis in April 1994. Endoscopy revealed lesions of early gastric cancer and duodenal ulcerations. A penetrating parasite into the duodenal mucosa was picked out, and identified as E. hortense. As the patient was treated with praziquantel 10 mg/kg single dose, 3 more E. hortense and 7 Metagonimus worms were recovered. This case demonstrates that echinostomiasis causes gross ulcerations in the duodenum.


Fig. 1
Fiberendoscopic wiews of the duodenum wall posterior to the bulb. A. moving worm (arrow) is penetration into the wall. B. The mucosal surface is obviously ulcerated after removal of the worm (arrow). Twon nearby ulcers are of same nature.

Figs. 2-4
Fig. 2. The worm removed from the duodenum by fiberscopy was identified as E. hortense. The worm was sectioned sagittally, showing head crown, large ventral sucker, uterine loop, ovary at equatorial dorsum, two testes at posterior body half, and vitelline follicles at ventral posterior body. Bar, 1 mm. Fig. 3. Magnified anterior end of the sectioned worm. The head crown (arrow) with collar spines (arrow heads) is well-developed, and tegumental spines are obvious. Fig. 4. three more E. hortense and 7 Metagonimus, Miyata type, were recovered from the case after praziquantel treatment. Gross view.

1. Bindseil E, Christensen NO. Thymus-independent crypt hyperplasia and villous atrophy in the small intestine of mice infected with the trematode Echinostoma revolutum. Parasitology 1984;88(Pt 3):431–438.
2. Chai JY, Huh S, Yu JR, Kook J, Jung KC, Park EC, Sohn WM, Hong ST, Lee SH. An epidemiological study of metagonimiasis along the upper reaches of the Namhan River. Korean J Parasitol 1993;31(2):99–108.
3. Gavet MF, Fried B. Infectivity, growth, distribution and acetabular attachment of a one-hundred metacercarial cyst inoculum of Echinostoma trivolvis in ICR mice. J Helminthol 1994;68(2):131–134.
4. Huffman JE, Michos C, Fried B. Clinical and pathological effects of Echinostoma revolutum (Digenea: Echinostomatidae) in the golden hamster, Mesocricetus auratus. Parasitology 1986;93(Pt 3):505–515.
5. Kim S, Fried B. Pathological effects of Echinostoma caproni (Trematoda) in the domestic chick. J Helminthol 1989;63(3):227–230.
6. Lee SH, Noh TY, Sohn WM, Kho WG, Hong ST, Chai JY. [Chronological observation of intestinal lesions of rats experimentally infected with Echinostoma hortense]. Korean J Parasitol 1990;28(1):45–52.
7. Lee SK, Chung NS, Ko IH, Ko HI, Chai JY. [Two cases of natural human infection by Echinostoma hortense]. Korean J Parasitol 1986;24(1):77–81.
8. Lee SK, Chung NS, Ko IH, Ko HI, Sohn WM. [A case of natural human infection by Echinostoma cinetorchis]. Korean J Parasitol 1988;26(1):61–64.
9. Lee SK, Chung NS, Ko IH, Sohn WM, Hong ST, Chai JY, Lee SH. [An epidemiological suryey of Echinostoma hortense infection in Chongsong-gun, Kyongbuk province]. Korean J Parasitol 1988;26(3):199–206.
10. Poland GA, Navin TR, Sarosi GA. Outbreak of parasitic gastroenteritis among travelers returning from Africa. Arch Intern Med 1985;145(12):2220–2221.
11. Ryang YS. [Studies on Echinostoma spp. in the Chungju Reservoir and upper streams of the Namhan River]. Korean J Parasitol 1990;28(4):221–233.
12. Ryang YS, Ahn KY, Kim WT, Shin KC, Lee KW, Kim TS. [Two cases of human infection by Echinostoma cinetorchis]. Korean J Parasitol 1986;24(1):71–76.
13. Seo BS, et al. Seoul J Med 1983;21(1):21–29.
14. Seo BS, Hong ST, Chai JY, Lee SH. Studies On Intestinal Trematodes In Korea: VIII. A Human Case Of Echinostoma Hortense Infection. Korean J Parasitol 1983;21(2):219–223.
15. Seo BS, Lee SH, Chai JY, Hong SJ. Studies on intestinal trematodes in Korea XX. Four cases of natural human infection by Echinochasmus japonicus. Korean J Parasitol 1985;23(2):214–220.
16. Simonsen PE, Bindseil E, Koie M. Echinostoma caproni in mice: studies on the attachment site of an intestinal trematode. Int J Parasitol 1989;19(5):561–566.
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